Massachusetts Ramp-Up Program (MassRamp)

The deadline for the latest round of the Massachusetts Ramp Up Program is now passed. Applications are no longer being accepted.


Program Overview

The Massachusetts Ramp-Up Program (MassRamp) promotes excellence in innovative solutions in the life sciences ecosystem and aims to bridge the funding gaps associated with the long-life sciences R&D cycle and the high cost of translating research into commercially viable products.

MassRamp leverages federal resources by providing supplemental funding for companies who have been awarded Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) Phase I Federal Grants / Contracts to:

  • support activities that cannot be covered by a federal grant (such as IP protection);
  • provide additional resources when federal funds are insufficient to complete an approved federal project;
  • expand the scope of the federal grant provided that the proposal to MLSC is based on the same technology approved in the federal award.

A typical project will last up to 2 years.

The selection process will rely on meeting the minimum threshold federal criteria of project significance, sound approach, innovation, capable investigators, and resources (as demonstrated by receiving a Phase I SBIR or STTR grant(s) or contract(s) from a federal agency), and a robust MLSC Scientific Advisory Board (SAB) evaluation. Proposals must focus on human health within an identified commercial product or service.

Program to Date

This is the inaugural round of the MassRamp Program. Up to $3,000,000 in funding is available for this round of the program. The Center will provide awardees with a grant of no less than $75,000 and no more than $300,000. Typical awards will be up to $200,000. The number of awardees and funding amount will be determined by the quality of the proposals.

Program Eligibility

  • The company must be a life sciences company in biotechnology, pharmaceuticals, medical devices, diagnostics or bioinformatics, located in and registered to do business in the Commonwealth of Massachusetts.
  • The company will have at least one Full Time Equivalent Employee (FTE) and no more than 30 FTE’s, the majority of whom based in Massachusetts.
  • The company must have been awarded a Phase I SBIR or STTR grant or contract from a federal agency for the project for which the company is requesting MassRamp funding. Having received a Phase II award (regular, direct or fast track) for the same project will disqualify it for this program.
  • Proposals must focus on human health with an identified commercial product or service.
  • Proposal to MLSC is based on a Phase I SBIR/STTR federal award with an initial Notice of Award dated after January 1, 2015
  • Companies that have active awards with the Center are not eligible to apply with the exception of companies that have received a Tax Incentive award or are participating in the Internship Challenge Program provided, however, that such companies are in compliance with those programs.
  • Applicants may submit more than one application, however only one award will be made per awarded company.

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