Massachusetts is a global leader in life science research and development. The Commonwealth also has a strong growing manufacturing presence. Many of the world’s top biotech, pharma, and medtech companies have chosen to co-locate their R&D and manufacturing operations in Massachusetts to take advantage of the density of talent, collaborative spirit, and opportunities for consistent iteration between the lab and production teams. These close collaborative connections work even better on the cutting-edge innovations when the manufacturing processes are nimble, creative, and responsive to the lightning speed of science.
The application period will run from Sept. 15 – Nov. 21, 2025 at 1 p.m. EST.
The MLSC’s BioBoost Manufacturing Scale-Up program supports companies creating or expanding their biomanufacturing or medtech advanced manufacturing presence in Massachusetts. This program aims to be a responsive and adaptive tool to fund capital investments, such as buildout, renovation, or equipment needs in a way that best meets current and future industry needs to support increased manufacturing activity and career development in Massachusetts. The BioBoost program will award funding of up to $3,000,000 per project in capital funding to support life science companies or partner nonprofits that can build or scale new manufacturing operations in Massachusetts. Separately, the BioBoost program will award funding of up to $500,000 per project to support real estate developers’ site readiness study or other planning/evaluation needs to develop a particular target property for life science manufacturing use.
Funding will be given to projects that can demonstrate a broader public benefit and contribute to the larger life sciences ecosystem including workforce training space and programming, offering access or discounts to small local companies, or collaboration with nonprofit partners.
The MLSC anticipates awarding up to three grants for direct manufacturing scale-up between $1,000,000 and $3,000,000 for two (2) years of work. The MLSC anticipates awarding one to two grants for real estate developer evaluation between $250,000 and $500,000 for one (1) year of work.
Company or non-profit applicants must use funds to create or expand biomanufacturing or medtech advanced manufacturing operations within Massachusetts, such as funding buildout, renovation, or equipment needs. Real estate developer applicants must use funds to conduct feasibility studies or otherwise assess specific site readiness for potential life science manufacturing purposes.
Applicants must be a:
BioBoost is open to life sciences companies of any size, based in Massachusetts or looking to expand to Massachusetts. BioBoost is also open to non-profit organizations, community colleges, universities, real estate developers, and municipalities.
Preference would be given for biomanufacturing or medtech advanced manufacturing operations that:
The BioBoost program was created to support life science companies seeking to manufacture their products in close proximity to their successful R&D operations, as well as to meet the needs of industry surveyed and evaluated in the spring of 2025, informed by recent shifts in the global economy and national focus.
Massachusetts has invested significantly in workforce development programs, such as Pathmaker, to support a diverse talent pipeline for skilled biomanufacturing and advanced manufacturing workers.
Olaris is a precision diagnostics company that is on a mission to revolutionize how diseases are diagnosed and treated. By leveraging their CEREBRO platform (Comprehensive Early Responsive Evaluation of Biomarkers Related to Outcomes), which combines metabolomics and machine learning, they are able to harness the power of the body’s own communication system to discover and develop their pipeline of myOLARIS precision diagnostics.
