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Novel Design Strategies for Effective Next-Generation Nuclear Localization Signal (NLS)-Therapeutics
In this technical session, Creative Biolabs has invited Dr. Leyton to describe the need to develop a more precise method in investigating nuclear transport dynamics of NLS-therapeutics. Moreover, Dr. Leyton will also present a de novo approach for generating novel NLSs with an atypical zero net-charge and evaluating various strategies to determine the worth for integration into NLS-therapeutics development.
During this webinar, we will discuss the following key points:
• Why nuclear targeting improves drug efficacy
• How nuclear transport functions
• What are the significant challenges for pharmaceuticals targeting the nucleus