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Research Infrastructure and Equipment

The MLSC is running two programs designed to provide grants for capital projects that support the life sciences ecosystem in Massachusetts by enabling and supporting life sciences research and development in the Commonwealth.

The application period will run from Aug. 4 – Nov. 21, 2025 at 1 p.m. EST.

Program Overview

The MLSC is running two programs designed to provide grants for capital projects that support the life sciences ecosystem in Massachusetts by enabling and supporting life sciences research and development in the Commonwealth. The two programs are the Research Infrastructure Program and the Research Equipment Program.

Research Infrastructure: Capital dollars are available to support capital projects ranging from $1.5 – $5 million to establish critical research resources across the state for not-for-profit organizations. Applicants will have to demonstrate how the requested infrastructure will benefit the entire life sciences ecosystem in Massachusetts.

Research Equipment: Capital dollars are available to support research equipment up to $500,000 across the state for not-for-profit organizations. Applicants will have to demonstrate how the requested piece(s) of equipment will benefit the entire life sciences ecosystem in Massachusetts.

Upcoming Info Sessions

Eligibility & Evaluation

Applicants must be a Massachusetts legally organized “not-for-profit” entity such as an academic/research institution, a hospital engaged in research, business incubator or accelerator, or other not-for-profit entity that would be eligible for capital funding from the Commonwealth of Massachusetts. Institutions that are exclusively health care providers and/or requests for the purchase of equipment associated with standard healthcare would not be eligible for capital funding.


Eligible applicants must meet the following criteria:

Applications must be submitted online. The MLSC staff will conduct an initial screening for application completeness and then submit applications to a panel of external experts for review. Applicants may receive invitations to present their proposals to address questions or provide clarification. The MLSC will provide final recommendations to its Board of Directors for approval.

Program Resources

Please note that the submission system only allows one active application per grant program at a time for each user account. It is possible to have an active application across multiple programs, as well as submit applications for the same program sequentially.

Impact on the Ecosystem

Massachusetts recognizes that investment in capital projects and infrastructure is required to create and sustain the attributes that make Massachusetts attractive to innovation clusters.  To date, the MLSC has awarded or committed more than $615 million to support capital research infrastructure projects across the state.

Learn more about the 2020, 2021, 2022, 2023, and 2024 Research Infrastructure awardees.

Connect with us to learn more

If you have any questions regarding the application process, e-mail: ResearchInfrastructure@masslifesciences.com.
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